{"id":24838,"date":"2020-12-16T09:04:42","date_gmt":"2020-12-16T08:04:42","guid":{"rendered":"https:\/\/inlab.fib.upc.edu\/projecte\/pasnas-drug-discovery-platform-by-abac\/"},"modified":"2025-11-17T11:32:04","modified_gmt":"2025-11-17T10:32:04","slug":"pasnas-drug-discovery-platform-by-abac","status":"publish","type":"projecte","link":"https:\/\/inlab.fib.upc.edu\/en\/projecte\/pasnas-drug-discovery-platform-by-abac","title":{"rendered":"PasNas drug discovery platform for ABAC"},"content":{"rendered":"","protected":false},"author":1152,"featured_media":6770,"template":"","meta":{"_acf_changed":false},"experteses":[8],"tencnologies":[642,602,483],"class_list":["post-24838","projecte","type-projecte","status-publish","has-post-thumbnail","hentry","experteses-datascienceandbigdata-en","tencnologies-matplotlib-en","tencnologies-pandas-en-2","tencnologies-python-en"],"acf":{"minidescripcio":"Development of a proprietary drug discovery platform to identify new antibiotics aimed at combating multi-resistant bacteria.","ordre_prioritat":9,"descripcio":"The inLab FIB collaborates with the company ABAC Therapeutics in the development of its own drug discovery platform to identify new antibiotics aimed at combating multi-resistant bacteria.\n\nThe dramatic increase in multidrug-resistant gram-negative (MDR) infections is of particular concern and represents a serious clinical burden in terms of prevalence, mortality and healthcare costs.\n\nIncremental improvements in existing broad-spectrum antibiotics are no longer able to keep up with the evolution of resistance.\n\nFinding new antibacterials is not easy since the molecular mechanism of action of the latest broad-spectrum antibacterials is 40 years old, despite the enormous efforts made in pharmacy to find new agents.\n\nABAC Therapeutics researches to find therapeutic solutions for patients infected with highly antibiotic-resistant bacterial pathogens that leave affected patients with few (or no) treatment options.\n\nNational health service chiefs, infectious disease professional organizations and infectious disease experts warn we are facing a return to a pre-antibiotic era and infections with these \"superbugs\" are increasing in both severity and frequency, and new ones are now needed medicines to treat them.\n\nPathogen-specific antibiotics represent an innovative approach to developing anti-infective drugs and have the potential to lead to a whole new generation of antibiotics.\n\nThe search for products with specific activity for each pathogen, together with the PasNas discovery platform, offers us a new paradigm for treating infections, based on precision antibacterial agents.\n\nABAC Therapeutics researches in a new line that allows identifying compounds with specific activity with new mechanisms of action, respectful of the human bacterial flora and at the same time minimizing the selection of resistant strains.\n\n\u00a0\n\nPoster summarising the project:\n\n<img class=\" size-full wp-image-6773\" style=\"width: 424px; height: 600px;\" src=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2020\/12\/9-_abac_poster_pizzaday_page-000.jpg\" alt=\"\" width=\"424\" height=\"600\">","image":"[caption id=\"attachment_14171\" align=\"alignleft\" width=\"300\"]<a href=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/800px-staphylococcus_bacteria.jpg\"><img class=\"size-medium wp-image-14171\" src=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/800px-staphylococcus_bacteria-300x169.jpg\" alt=\"Staphylococcus bacteria\" width=\"300\" height=\"169\" \/><\/a> Staphylococcus bacteria[\/caption]\r\n\r\n[caption id=\"attachment_14174\" align=\"alignleft\" width=\"202\"]<a href=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/salmonella_bacteria_5613656967.jpg\"><img class=\" wp-image-14174\" src=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/salmonella_bacteria_5613656967-300x251.jpg\" alt=\"Salmonella bacteria\" width=\"202\" height=\"169\" \/><\/a> Salmonella bacteria[\/caption]\r\n\r\n[caption id=\"attachment_14177\" align=\"alignleft\" width=\"200\"]<a href=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/600px-neisseria_meningitidis_charles-orszag_2018.png\"><img class=\" wp-image-14177\" src=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/600px-neisseria_meningitidis_charles-orszag_2018-300x300.png\" alt=\"Neisseria meningitidis bacteria\" width=\"200\" height=\"200\" \/><\/a> Neisseria meningitidis bacteria[\/caption]\r\n\r\n&nbsp;\r\n\r\n&nbsp;\r\n\r\n&nbsp;\r\n\r\n&nbsp;\r\n\r\n&nbsp;\r\n\r\n&nbsp;\r\n\r\n&nbsp;\r\n\r\n[caption id=\"attachment_14180\" align=\"alignleft\" width=\"245\"]<a href=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/800px-streptococcus_pneumoniae_-_a_causative_bacteria_of_meningitis.jpg\"><img class=\" wp-image-14180\" src=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/800px-streptococcus_pneumoniae_-_a_causative_bacteria_of_meningitis-300x169.jpg\" alt=\"Streptococcus pneumoniae a causative bacteria of meningitis\" width=\"245\" height=\"138\" \/><\/a> Streptococcus pneumoniae a causative bacteria of meningitis[\/caption]\r\n\r\n[caption id=\"attachment_14183\" align=\"alignleft\" width=\"201\"]<a href=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/helicobacter-pylori_0.png\"><img class=\" wp-image-14183\" src=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/helicobacter-pylori_0-300x204.png\" alt=\"Helicobacter Pylori\" width=\"201\" height=\"137\" \/><\/a> Helicobacter Pylori[\/caption]\r\n\r\n[caption id=\"attachment_14186\" align=\"alignleft\" width=\"244\"]<a href=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/salmonela.png\"><img class=\" wp-image-14186\" src=\"https:\/\/inlab.fib.upc.edu\/wp-content\/uploads\/2022\/12\/salmonela-300x170.png\" alt=\"Salmonel\u00b7la\" width=\"244\" height=\"138\" \/><\/a> Salmonel\u00b7la[\/caption]","url":"","data_inici_pro":"20200715","data_fi_pro":"20221215","client":[19383],"entitat_finan":null,"colab":[19369],"responsable":[8],"equip":[1044,1096,1172,1143,1166],"escert":"0","mpi":"0","accio":"0","padih":"0","nacional":"0","participants":"","participants2":"","projecte_final":null,"articles_presentacions":"<ul>\r\n \t<li><a href=\"https:\/\/www.upc.edu\/ca\/sala-de-premsa\/noticies\/abac-therapeutics-i-la-upc-busquen-noves-molecules-per-fer-front-als-bacteris-resistents-als-antibiotics\" target=\"_blank\" rel=\"noopener\"><span style=\"font-size: 13px;\">ABAC Therapeutics i la UPC busquen noves mol\u00e8cules per fer front als bacteris resistents als antibi\u00f2tics<\/span><\/a>\u00a0 (Premsa UPC)<\/li>\r\n \t<li><a href=\"https:\/\/www.lavanguardia.com\/vida\/20220429\/8232342\/cientificos-buscan-moleculas-bacterias-resistentes-antibioticos.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-size: 13px;\">Cient\u00edficos buscan mol\u00e9culas contra las bacterias resistentes a antibi\u00f3ticos<\/span><\/a>\u00a0(La Vanguardia)<\/li>\r\n \t<li><a href=\"https:\/\/www.eleconomista.es\/salud\/noticias\/11742201\/04\/22\/Las-matematicas-son-la-nueva-arma-en-la-lucha-contra-las-resistencias-a-los-antibioticos.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-size: 13px;\">Las matem\u00e1ticas son la nueva arma en la lucha contra las resistencias a los antibi\u00f3ticos<\/span><\/a>\u00a0(El Economista)<\/li>\r\n \t<li><a href=\"https:\/\/www.pmfarma.es\/noticias\/33974-abac-therapeutics-y-la-upc-buscan-nuevas-moleculas-para-hacer-frente-a-las-bacterias-resistentes-a-los-antibioticos.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-size: 13px;\">ABAC Therapeutics y la UPC buscan nuevas mol\u00e9culas para hacer frente a las bacterias resistentes a los antibi\u00f3ticos<\/span><\/a>\u00a0(PMFarma)<\/li>\r\n \t<li><a href=\"https:\/\/fotos.europapress.es\/fotonoticia\/f4414440\" target=\"_blank\" rel=\"noopener\"><span style=\"font-size: 13px;\">Empresas.- ABAC Therapeutics y UPC buscan nuevas mol\u00e9culas para hacer frente a las bacterias resistentes a antibi\u00f3ticos<\/span><\/a>\u00a0 (Europa Press)<\/li>\r\n \t<li><a href=\"https:\/\/xafir.cat\/2023\/02\/01\/video-plataforma-de-descobriment-de-farmacs-pasnas\/\" target=\"_blank\" rel=\"noopener\">V\u00eddeo: Plataforma de descobriment de f\u00e0rmacs PasNas (Xarxa Xafir d'Ind\u00fastria 4.0 de Catalunya)<\/a><\/li>\r\n<\/ul>","slideshare":""},"_links":{"self":[{"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/projecte\/24838","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/projecte"}],"about":[{"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/types\/projecte"}],"author":[{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/users\/1152"}],"acf:user":[{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/users\/1166"},{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/users\/1143"},{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/users\/1172"},{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/users\/1096"},{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/users\/1044"},{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/users\/8"}],"acf:post":[{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/empresa\/19369"},{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/empresa\/19383"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/media\/6770"}],"wp:attachment":[{"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/media?parent=24838"}],"wp:term":[{"taxonomy":"experteses","embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/experteses?post=24838"},{"taxonomy":"tencnologies","embeddable":true,"href":"https:\/\/inlab.fib.upc.edu\/en\/wp-json\/wp\/v2\/tencnologies?post=24838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}